ON-DEMAND WEBINAR
Strategies for Oligonucleotide Drug Delivery and Detection
Join this webinar to hear from leading experts, Aimee L. Edinger, VMD/PhD and Carl A. Ascoli, PhD, who will discuss cutting-edge advancements in the field of oligonucleotide drug delivery and detection. Learn how to overcome the hurdle of inefficient endosomal escape for oligonucleotide therapeutics with an approach that uses a synthetic sphingolipid analog to enhance the activity of antisense oligonucleotides and small interfering RNAs without causing endosomal permeability. In addition, you'll be introduced to a revolutionary panel of universal detection reagents designed to detect specific chemical modifications for the collection of ADME analytical data.
Key topics include:
Inhibition of endocytic recycling and lysosomal fusion
Methods to enhance the activity of antisense oligonucleotides and small interfering RNAs by up to 100x
Challenges that hinder oligonucleotide therapeutic drug development
Analytical tools for assessing drug performance and safety
Presenters:
Aimee L. Edinger, VMD/PhD
Dept. of Developmental and Cell Biology - UC Irvine
Aimee Edinger is a Professor of Developmental and Cell Biology, Chancellor’s Fellow, and AAAS Fellow at UC Irvine. She is also the Associate Director of the UCI Cancer Research Institute and co-Director of the NCI T32 Training Grant, supporting interdisciplinary training at UCI.
Carl Ascoli, PhD
Chief Science Officer - Rockland
Dr. Carl Ascoli brings over 30 years of experience to Rockland and is responsible for leading teams in production, research, quality, and service. His guidance has led to the development of thousands of antibodies, many of which have been translated into assays and biomarker discoveries for cancer and other areas of research.